WebBy Xianju Bi , Yanhui Xu , Xinmin S. Li , Wenzhi Li. Cell. Highlights • RNA-binding protein WDR43 coordinates hyperactive transcription and ribogenesis • Nascent RNA and transcription target WDR43 to open chromatin • Chromatin recruitment of WDR43 positively feeds back on transcription elongation • WDR43 promotes Pol II release ... WebCells 2024, 9, 1406; doi:10.3390/cells9061406 www.mdpi.com/journal/cells . Article . Cell Type-Specific In Vitro Gene Expression Profiling of Stem Cell-Derived Neural ...
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Web2013) suggest that defects in RNA processing lead to neurodegeneration. In the case of C9ALS, sequestration of RNA-binding proteins by the transcribed G 4C 2 expansion is a proposed pathogenic mechanism, and it has been shown that RNA from this locus forms intranuclear foci in the brains of affected individuals (Donnelly et al., 2013). WebThe IPed RNAs and WCE RNAs were then treated with Turbo DNase (Life Technologies) to remove potential DNA contamination. Reverse transcription was performed using the … great lakes data \u0026 analytics summit
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