WitrynaDOI: 10.3389/fgene.2024.1096616 Corpus ID: 257927872; Clinical efficacy of Yiqi Yangxue formula on knee osteoarthritis and unraveling therapeutic mechanism through plasma metabolites in rats Witryna24 gru 2024 · The protective effects of chlorogenic acid (CGA) against liver injury were evaluated by its reduction in carbon tetrachloride (CCl4)-induced hepatic damage in ICR mice. The animals were orally given CGA (60, 100, and 200 mg/kg, respectively) or silymairn (200 mg/kg) daily with 0.3% CCl4 administration (3 mL/kg, dissolved in olive …
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WitrynaReduced glutathione (GSH, l-glutamyl-l-cysteinyl-glycine), a tripeptide composed of amino acids glutamate, cysteine, and glycine, is the most abundant low-molecular … WitrynaGSH is synthesized from cysteine via sequential enzymatic reactions involving the rate-limiting γ ... It downregulates GSH and GPX4 while inducing ROS and cell death, which can be blocked by ferrostatin-1, necrostatin-1, and z-VAD-FMK. ... Ichijo, H. Iron homeostasis and iron-regulated ROS in cell death, senescence and human diseases. … flower of may campsite filey
Figure 8 from Clinical efficacy of Yiqi Yangxue formula on knee ...
WitrynaIn vivo two-photon laser scanning microscopy was used to image cell death in injured parenchyma in each mouse over a 12-hour period (at 1, 3, 6, and 12 hours). ... The concentrations of ROS and GSH were evaluated by measurement of the absorbance at 560 nm for ROS and 420 nm for GSH. ... Images were collected using sequential … WitrynaRecently, the usage of mesenchymal stem cells (MSCs) has been investigated to improve liver fibrosis. It has been reported that the differentiation, proliferation and … WitrynaMany of the pathophysiological effects of RONS may occur simultaneously or sequentially. Therefore, imbalanced RONS ... oxidative stress has been proved as … green ampt infiltration model